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Norepinephrine (along with dopamine) plays a large role in attention and focus. Our adrenal glands manufacture the hormone which is then released into the blood stream. When you increase the levels of norepinephrine in the body, you become more alert and focused. Strattera is a “selective norepinephrine reuptake inhibitor” which is unique in that it does not alters dopamine levels (hence less abuse potential) but does increase norepinephrine levels at nerve synapses for nerve impulses transmission. As a stress hormone, norepinephrine affects parts of the brain where attention is controlled. It initiates our survival fight-or-flight response, increasing heart rate, triggering release of glucose into blood stream, and increasing muscle readiness.