OPIOID DOSING FOR EQUIVALENT ANALGESIA

Drug

Dosage

Morphine (Immediate release)

10mg q4h

Morphine (Controlled release – e.g. MS Contin, Kadian)

30mg q12h

Hydromorphone (Immediate release – e.g. Dilaudid)

2 – 4mg q4h

Hydromorphone (Controlled release – e.g. Hydromorph Contin)

6mg q12h

Hydromorphone (Extended release – e.g. Jurnista)

12mg q24h

Oxycodone (Immediate release – e.g. Oxy IR, Percocet)

5 – 10mg q4h

Oxycodone (Controlled release – e.g. Oxy Contin)

20 – 30mg q12h

Oxymorphone (Immediate release – e.g. Opana)

5mg q6h

Oxymorphone (Extended release – e.g. Opana ER)

10mg q12h

Hydrocodone (Immediate release – e.g. Vicodin)

10 – 15mg q4h

Codeine

60mg q4h

Methadone

Variable – patient tolerance, short-term vs chronic dosing; approx. 7.5mg/24h

Meperidine

50mg q4h (Acute use only: <48 hrs )

Fentanyl patches

25 µg/hr