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Eli Lilly Canada, maker of Evista, released a statement regarding increased mortality rate due to stroke, albert just slightly, in postmenopausal women on Evista. Evista is a popular and effective drug to prevent osteoporosis in menopausal women. Women enrolled in the RUTH trial had either documented coronary heart disease, lower extremity arterial disease, hypertension, diabetes mellitus, hyperlipidemia, tobacco smoking, or age 70 and over. Women with a history of stroke or stroke risk factors such as transient ischemic attack or atrial fibrillation should be carefully assessed before put on Evista.