OPIOID RECEPTORS & THEIR ACTIONS
|
|
Mu |
Kappa |
Delta |
Nociceptin |
|
Pain relief |
Yes |
Yes |
Yes |
|
|
Respiratory depression |
Yes |
|
|
|
|
Reduced GI motility |
Yes |
|
|
|
|
Miosis |
Yes |
Yes |
|
|
|
Euphoria |
Yes |
|
|
|
|
Physical Dependence |
Yes |
|
Yes |
|
|
Sedation |
|
Yes |
|
|
|
Dysphoria |
|
Yes |
|
|
|
Inhibition of ADH release |
|
Yes |
|
|
|
Antidepressant |
|
|
Yes |
|
|
Convulsion |
|
|
Yes |
|
|
Anxiety |
|
|
|
Yes |
|
Depression |
|
|
|
Yes |
|
Appetite |
|
|
|
Yes |
|
Tolerance |
|
|
|
Yes |